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OJVRTM
Online
Journal of Veterinary Research©
Volume 13
(1):106-110, 2009
Effect of Echinacea
on antibody titres induced by Peste des Petits Ruminants (PPR)
vaccine
in sheep.
El-Dakhly AT, Al-Asadiy YD, Azab AE, Alnagaz RI.
Department of Biology, Faculty of
science (Augylat), University of 7th of April –
ABSTRACT
El-Dakhly AT, Al-Asadiy YD, Azab AE, Alnagaz
RI., Effect of Echinacea on
antibody titres induced by Peste
des Petits Ruminants (PPR) vaccine in sheep, Online J Vet Res, 13
(1):106-110, 2009. Echinacea angustifolia may enhance immune function
by increasing antigenic-specific immunoglobulin production. This study was
conducted to determine the possible immuno-stimulatory effect of Echinacea
extract when given with PPR vaccine in sheep. Four groups of 5 sheep each were
administered orally with PPR vaccine (control), and 100%, 60% and 20% with
super critical carbon dioxide (SCD), ethanolic extract of Echinacea, (EE)
respectively. Blood samples were collected from each animal at 7, 14, 21, 28
and 35 days for serum separation. Antibody titre was estimated by ELISA and serum neutralizing test (SNT). The
highest titre of antibodies was observed in animals treated with 60% and 20% EE
which suggests that EE improved the response of the immune system to PPR.
Key words: Echinacea, antibody titres, Peste des Petits Ruminants (PPR) vaccine, sheep.