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OJVRTM
Online Journal of Veterinary Research©
Volume
8:33-41, 2004.
Response of equine
articular cartilage to a single impact load.
Bowe EA, Henson FMD*, Caddick J, Jeffcott LB, Davies ME.
Department
of Clinical Veterinary Medicine,
ABSTRACT
Bowe EA, Henson FMD, Caddick J, Jeffcott LB, Davies ME., Response of equine articular cartilage to a single impact load. Online J Vet Res,
8: 33-41, 2004. The aim of this
study was to investigate the damage caused to equine articular cartilage by a
single impact load applied using a simple drop tower device. An impact
load (500g) caused histological changes including fissure formation, disruption
of the articular surface and loss of proteoglycan content, which were more
marked at a drop height of 10cm compared to 2.5cm. The damage caused by a
single impact load from a height of 2.5cm was comparable to that previously
reported in exercised horses and in clinical cases of degenerative joint
disease. These results indicate that the method of single impact load in
cartilage may have potential in the in
vitro investigation of equine cartilage damage.
KEY WORDS: Equine,
cartilage, load, osteoarthritis