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Online Journal of Veterinary Research ©
Evaluation of anthelminths on sheep nematodes in Ethiopia
Tadesse Eguale1 Hassen Chaka2 and Daniel
Gizaw2, Demeke Sibhatu2
1Aklilu
lemma Institute of Pathobiology, Addis Ababa University
and 2National Animal Health
Diagnostic and Investigation Center, Ministry of Agriculture and Rural
Development, Sebeta, Ethiopia
ABSTRACT
Eguale T, Chaka H, Gizaw G, Sibhatu D, Evaluation of anthelminths
on sheep nematodes in Ethiopia, Online J Vet Res., 14
(2): 270-276, 2010. Albendazole, tetraclozan and tetramisole were evaluated
against sheep nematodes in Ethiopia. Animals were balanced for fecal egg count
(FEC), and fecal egg count reduction tests (FECRT) were performed. There was a 99-100% reduction in the FEC 10 days with albendazole and tetraclozan and 93.1% with tetramisole (in
one locality). The efficacy of tetramisole and
tetraclozan varied between localities but there was
no significant difference (p>0.001) in mean fecal egg count. No eggs were
found 10 days post-treatment in albendazole treated
groups, but some were found in tetraclozan and tetramisole treated sheep. The
results suggest that there may be some localized resistance to tetramisole. Continuous monitoring is required to avoid inducing
helminth resistance.
Key words: - Anthelmintics;
Efficacy; Nematodes; Sheep; Resistance