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Online Journal of Veterinary Research
Volume 1:7-28, 2002 .
Immunohistochemical localization of substance P, calcitonin gene-related peptide, galanin and calcium binding proteins in myenteric and submucosal plexuses of goat small intestine
In Koo Hwang (DVM, MS), Heungshik S Lee (DVM, PhD), Young Sam Nam (DVM, BS), Choong Hyun Lee (DVM, MS), Yeo Sung Yoon (DVM, PhD), Tae-Cheon Kang* (DVM, PhD), Moo Ho Won* (DVM, PhD), In Se Lee+ (DVM, PhD).
of Anatomy, College of Veterinary Medicine and School of Agricultural
Biotechnology, Seoul National University, Suwon, Kyunggi-Do, *Department of Anatomy, College of Medicine, Hallym University. Chunchon, Kangwon-Do, Dr. In Se Lee,
Department of Anatomy,
In Koo Hwang, Heungshik S Lee, Young Sam Nam, Choong Hyun Lee, Yeo Sung Yoon, Tae-Cheon Kang, Moo Ho Won, In Se Lee., Immunohistochemical localization of substance P, calcitonin gene-related peptide, galanin and calcium binding proteins in myenteric and submucosal plexuses of goat small intestine. Online J Vet Res 1: 7-28, 2002. Immunohistochemical and double immunofluorescent was used to identify the localization of calbindin D-28k (CB), calretinin (CR), parvalbumin (PA), substance P (SP), calcitonin gene-related peptide (CGRP) and galanin (GAL) in the goat small intestine. Localization of CB with SP, CGRP or GAL in the myenteric and submucosal plexuses suggests that CB may serve a neuromodulatory role for SP-, CGRP-, and GAL-immunoreactive neurons in intestinal wall motility. Distributions of CB, CR and SP of the goat small intestine differ from guinea-pig and the pig. This difference may be relevant to morphological characteristics.
KEY-WORDS: Calbindin, calretinin, parvalbumin, calcitonin, gene peptide, localization, small intestine, goat.